Is it possible to write a game that, through system-link and eventually X-Box Live, could accomadate more than 4 X-Box's and thus more than a maximum of 16 people?

Obviously unless it were on a LAN a sytem link game w/ more than 4 boxes would lag in most, but not all, cases, but what about x-box live? All the articles about games that are to come out this spring or later seem to indicate that a maximum of 16 players can be accomadated.

If more than 16 could play, that would be very cool.