Ok first off let me say I don't know if this works all over the place, but in Lord of the Rings: War in the North I've found a place that allows you to re-open chests and in a sense build a ton of cash and obtain some amazing weapons and armor. Now while the loot is random, every attempt at this will earn you something to sell at least for tons of coins.
Early on in the game you will have to venture to a camp called Sarn Ford, there you will take on a quest to go to The Barrow Downs. You will reach a point called Barrow of Amon Gorthad where you will have a portal to return to San Ford on your right hand side and a portal to continue on on the wall next to it. In this room you will find a chest, some breakable objects, and an armor pile that you can loot for items.
After you collect everything in this room, use the portal to go back to the camp at Sarn Ford. Once you get back, work your way through the camp again and take the portal that leads you back to The Barrow Downs. When you arrive you'll be right back in the room in the Barrow of Amon Gorthad. When you enter the room again you'll notice that the chest, armor pile and breakable objects have all reset.
Loot the room again, take the teleport back to the camp at Sarn Ford, rinse and repeat and you can obtain tons of loot that you can either use or sell.
I haven't tried this option anywhere else in the game yet, but the load times and the trip through the camp take the longest.